Allergies in dogs and cats:
When I first graduated as a vet 20 years ago, I concept I knew how to treat every disease in animals known to man. A few years in suburban practice fast taught me the error of my thinking - and the many stumbling block I ever came across, was trying to treat skin allergies in dogs and cats. I fast realized that the side effects of most of my treatments were rapidly becoming worse than the former disease itself. It was with this back ground that I was impelled to look deeper, to look for the un-seen cause of allergies.
Allergies are basically an "inappropriate" or "over-zealous" reaction of an animals' (or persons) immune system. The reaction is caused by exposure to safe bet chemical or organic agents, generally referred to as "allergens". Genetics categorically play a role in pre-disposing an animal to developing allergies, but environment and cusine will finally decree to what degree the allergy is expressed.
Allergies in pets fall into some separate categories, but nearly all allergies have a base expression - lasting allergic skin disease (allergic dermatitis or "eczema"). Allergies can be triggered by airborne allergens (atopic dermatitis), by direct feel with the skin (contact allergy), by exposure to safe bet foods (food allergy), or by exposure to parasites (eg flea allergy dermatitis). The pattern of skin disease can vary widely, but subtle differences can help to decree what type of allergy is involved. The classic signs of allergy include generalized itching, feet chewing, face and muzzle rubbing, dermatitis of the inner legs, abdomen and armpits, lasting ear infections, "hot spots", and more recently, asthma in cats.
Traditional veterinary treatments for allergic skin disease have included using drugs like cortisone, anti-biotics, anti-histamines, ant-parasitic agents, and topical medicated shampoos. The good old "bucket on the head", known more professionally as an Elizabethan collar, has also been widely used to prevent self trauma. More recently, testing for known allergens has become popular, and the use of de-sensitisation (gradual exposure to diluted forms of the known allergen) has shown some success. Recognition of the role of primary fatty acids (primarily Omega 3 fatty acids), and their inclusion as a dietary additive, has also shown some promise. But on the whole, allergic skin disease is still one of the most common, and frustrating, veterinary complaints that brings pet owners to the waiting room. One unfortunate reality of allergies is that despite all the advances in contemporary medicine, allergies are still determined a "chronic" disease - meaning that there is no "cure" for an allergy, the best we can hope to do is "control" the expression of an allergy, and limit the use of drugs required to do so.
Understanding the Immune system:
The key to "controlling" allergies is to understand how and why they occur. As mentioned, allergies are an inappropriate immune reaction to a specific allergen - a reaction that that is not "pre-programmed" into the immune ideas by the core genetic code, but one that is "learned" or "accidentally" occurs. The study of the immune ideas (immunology) is a captivating science, and one that has provided much of the facts that is driving contemporary healing advances. One of the captivating facts about the immune system, is that it works in almost the same way in all animal species- from man to fish. It is an old and untouched genetic code, and is designed to "protect" an animal from disease, and to aid repair.
A approved description of how the immune ideas works is beyond the scope of this article, but a very simplified overview will aid in insight allergies. In very rough terms, the immune ideas can be divided into 2 parts. One part is complex in making antibodies - cells that yield extra proteins that are specifically designed to "recognize" specific foreign molecules (eg bacteria or viruses) which are called "antigens". The body has millions of separate cells (B lymphocytes) which yield separate types of antibodies which safe us from infection, and these antibodies form the basis of the practice of immunization (where we introduce non-dangerous parts of a bacteria or virus so the body can make antibodies to that singular pathogen). The second part of the immune ideas is known as the "innate" immune system, and it involves cells that we generally call "white blood cells". These cells are responsible for directly destroying foreign agents, infected cells, or antibody/antigen complexes formed by the other part of the immune system. When your body is under strike by a bacteria or virus, these cells poor into the blood stream to fight off the agent, and the supervene is that on a blood test, you have a "high white blood cell count". As white blood cells capture and destroy these foreign particles, they categorically die themselves, and the resultant protein sludge that remains is known as pus (when concentrated in a small area).
In an allergic reaction, we have an "accidental" response. Lets use the example of an inhaled grass pollen. Commonly the immune ideas should not recognize the grass pollen as foreign or dangerous (we inhale limited pollens all the time while spring and summer). But in an allergic response, for some think the immune ideas creates a specific antibody to the pollen. This antibody seeks out the pollen, and binds to it. Then, a singular part of the innate immune ideas (white blood cells known as "eosinophils") are released into the blood to capture and destroy these antibody/antigen complexes. When these eosinophils have done their job, they also "die", but as the cells burst, they publish histamine - which causes intense local swelling and itching. In people, this reaction generally occurs locally, at the location of the nose and eyes where the pollen first contacts the moist mucus membranes - and results in "hay fever symptoms" (swollen itchy eyes and nose, sneezing etc). If the reaction occurs deeper in the body, at the level of the bronchi in the lungs, it can cause "asthma". In dogs and cats, these cells categorically migrate to the skin (and sometimes to the lining of the gut) where they cause an intense itching reaction which we call allergic dermatitis. When the animal itches, it breaks the skin, and allows secondary infection to occur, which added adds to the irritation - and so the cycle goes on.
The pattern of allergies is determined by the type of allergen. Some allergies are seasonal, meaning that the allergen is only in the environment for a specific time of the year - most of these are caused by plant pollens etc (called atopic allergies). Some feel allergies, like grass allergy only occur when grasses are dry and producing seed heads, and most of the signs occur on the underneath of the dog, in areas where there is no fur protecting the skin (eg groin, armpits, belly). If the allergen is present all year round, such as a food allergy (to a specific food type) or allergies to dust mites, then the signs of allergic dermatitis will be constant.
So what causes the Immune ideas to malfunction?:
The sass to this quiz, is the key to solving the difficulty of allergies, and unfortunately there is not one easy answer. A genetic predisposition (ie an inherited tendency) is categorically one big factor. safe bet breeds of dog (eg West Highland White Terriers) are genetically predisposed to developing allergies. Staffordshire terriers are prone to feel allergies, German Shepherds are prone to food allergies and lasting ear infections etc. But in veterinary practice, we are looking more and more dogs with allergies (probably the estimate one think people go to see their vet apart from vaccination), and genetics alone cannot be the answer.
Modern immunology has now shown us that both nutrition, and environment, will influence the way our immune ideas functions. When we talk about environment, we categorically mean the "artificial" environment, and the exposure to man made chemicals. In the house, pets may be exposed to chemical cleaning agents, carpet and floor products, insect sprays, deodourisers, perfumes etc. And outside, in the organery or on a walk, there are air pollutants (eg. Petrochemical fumes), weed sprays and herbicides, water pollutants (fluoride, chlorine) and a host of other "un-natural" potential allergens. And what about the products we deliberately use on our pets - shampoos, conditioners, worm tablets, flea and tick control, heartworm prevention, even the chemical stabilizers used in vaccines - all of these can act as potential "triggers" for allergies. Naturally some of these cannot be avoided, but we do need to exercise some care when we have an allergic pet. Other recognized triggers also include the huge range of chemical preservatives and colourings used in processed pet foods, some of which are now recognized as carcinogenic. Sulphur dioxide, a base preservative used in pet meat, is also a known trigger for asthma and eczema in people. It is leading to remember that most of these chemical agents are "new" to the immune ideas (they weren't colse to hundreds of millions of years ago when the immune ideas was evolving in fish), so it is not surprising that our bodies do react to them as "foreign".
Recent studies into immunology and parasites have also revealed some staggering results in this area. Dogs and cats have been evolving on earth for some 40 Million years, and for the first 39.98 Million years, they did so without interference from man. Their bodies had industrialized a natural equilibrium between intestinal and topical parasites, which was controlled by their immune system. The part of the immune ideas that controls parasites, are the same cells (eosinophils) that are complex in allergies. When these eosinophils react at the gut level, the publish of histamine categorically causes swelling and increased motility, which aids the elimination of gut parasites (worms). At the skin level, the publish of histamines causes itching, which in turn, aids the discharge of fleas. This process has kept the natural equilibrium of parasites in check for millions of years. With the advent of contemporary chemical worming tablets and the farranging adoption of 3 monthly worming programs, intestinal worms have become a thing of the past. To added add to this, contemporary "all in one" topical preparations that control topical parasites and heartworm, also kill the majority of intestinal worms, but on a monthly basis. Whilst this may at first appear to be a great thing for our pets (and don't get me wrong, these products are very useful), we have now reached a position where our pets can be completely "sterile" of all parasites.
What contemporary immunology has discovered however, is that when the body is sterile of parasites, the part of the immune ideas that has evolved over millions of years to control them, the eosinophils, is now left without a job to do - and as a result, there are now large numbers of these cells available to react to "allergens". What this means is that the supervene of an allergic reaction in pets that have no parasites to control, is categorically far more intense, than in a pet where these cells are categorically doing the job they were designed to do. In short, dogs and cats that are "sterile" are far more prone to having serious allergic skin disease.
And what of nutrition? How does what we eat, or what we feed our pets', influence the immune system? Most people nowadays do accept that what we eat will influence our farranging health and longevity, but what we may not realize is, that it affects our health by affecting our immune system. In easy terms, the better your immune ideas works, the better your every day health will be, and the longer you will live (excluding bad luck). contemporary cusine recognizes that there are 76 known macro and micro nutrients required for exquisite health. Naturally put, your immune ideas needs all 76 elements to function perfectly. What we also now understand, is that our bodies (and that of your pets') do not exist in a "sterile" environment. The intestinal tract requires the proximity of pro-biotic bacteria (often termed "good" bacteria) - names like acidophilus (the bacteria found in natural yogurt) are now generally recognized as being healthy. Our pets also have their own people of good bacteria, and they are also primary for good health. It is the compound of a diet that provides all the primary nutrients, combined with an intestinal tract full of pro-biotics, which allows our body to digest the nutritional value. And this finally ensures that the immune ideas receives all 76 of the elements required for it to function at its optimum.
Unfortunately, for both humans and pets, the supply of good, healthy food is no longer as easy as it used to be. Just two hundred years ago, people ate good quality fresh food. yield was grown organically, harvested and eaten. There was limited in the way of processing or preserving, and the soils that were used to grow crops, fruit, or livestock, were healthy and nutrient rich. Compare that to today, when an apple bought from the supermarket may be 9 months old before you eat it, and it has been grown entirely on artificial fertilizers and sprayed with chemicals, or the fact that the vitamin C content of a supermarket orange has fallen to 2% of what it was the day it was picked, and we see it is not so hard to understand what has gone wrong. If you add to that the processing and preservatives used to enlarge shelf life, and the over-abundance of sugars and salts included in processed food and drinks, we start to see an insidious pattern of contemporary day "malnutrition" emerging.
But don't think that you pet has been spared this reality. For the past 40 Million years, dogs and cats ate a healthy diet of wild prey, raw, uncooked and unprocessed, supplying not only the primary probiotic bacteria for gut health, but also the faultless 76 nutrients for exquisite health. But in contemporary society, we now know better, and pets' are fed on man's waste! On the whole, processed pet foods are made from in-edible carcass remains (made into meat meal and meat by-products), cheap sources of bulk carbohydrate and vegetable matter, sugar, salt, flavours, and preservatives. Add to this a cocktail of about 25 + chemically derived primary vitamins and minerals (a commercially available product which guarantees a pet food will meet Aafco nutritional standards). Then finally, mix all this into biscuits, cook at high temperatures (> 260'C for import into Australia), and then spray with liver digest and fat (so your pet will categorically eat it) - this is what has substituted the natural diet of dogs and cats.
Modern pet foods are sterile (they supply no pro-biotic bacteria) and they categorically do not supply the body with the 76 nutrients required for optimal health, no matter how much they cost, or what they say on the pack. Sure, there are much better ones, and much worse ones, but collectively, they are contributing to the same "modern day malnutrition" that is affecting western society. We are gently turning our pets into "junk foodies".
So back to allergies, how is all this causing allergies in pets? It is quite simple. The way immune cells react is categorically influenced by a wide range of nutritional factors, many of which contemporary science is yet to fully understand. We do know that if an animal's diet is deficient in Omega 3 primary fatty acids, the immune ideas will react in a more inflammatory way, producing more histamine publish and a greater "allergic" tendency, than compared to an animal that has an adequate dietary intake of Omega 3 fats. We also know that omega 3 fats are generally deficient in processed pet foods, or are categorically oxidized and rendered useless, by the processing and handling of dry and tinned pet food. And this is but one of the 76 elements that can influence the immune system. When we consolidate this type of deficiency, with other mal-nutritional factors caused by poor dietary ingredients and processing,a pattern emerges. Add the loss of pro-biotic bacteria, and the sterile gut caused by over zealous hanger-on control, and we have a "pro-allergic" state in the animal's immune ideas - which is just waiting to react.
So whereas the "healthy" body may have shown just a mild reaction to an allergen (say flea saliva from a flea bite) we suddenly have a weighty over-reaction to the introduction of a Commonly mild allergen - with wide scale publish of histamine and intense itching and chewing (and we end up with a dog with "hot spots"). If we consolidate all this with a living environment full of contemporary chemical agents and potential "triggers" (and in the food we feed our pets), then it is not hard to understand why we are looking such an "epidemic" of allergies in pets, and in people.
So what can we do?;
Certainly I do not pronounce to have all the answers to treating allergies, but there are some basic guidelines that I supervene in practice, that consistently lead to effective, safe bet results in pets that have allergies.
1. To best supply the primary pro-biotics and 76 elements, convert you pet onto a natural, raw, balanced and unprocessed diet, using fresh meats and yield that has not been treated with chemical preservatives (avoid sulphur dioxide = preservative 220, 221, 222 etc). Choose a meat source that your pet is not likely to have had regular entrance to (eg kangaroo meat, or tripe) - avoid chicken and beef. And stick to a easy carbohydrate, like rolled oats or brown rice. Eg. Vets All Natural superior Choice, or faultless Mix
2. Add the following daily supplements - a dose of pro-biotics (eg Protexin), an all natural multivitamin and mineral supplement, an Omega 3 fatty acid supplement such as Flax Seed oil or Fish oil (fish oil is better for cats). Eg. Vets All Natural health Booster and Omega Blend Oil.
3. When using hanger-on control, try to use products that only influence the hanger-on you are targeting. Eg, use a product that only kills fleas if you have a flea problem, or a product that only kills heartworm larvae, and not one that also kills intestinal worms. For regular worming, consider having a fecal test done to see if there are worms present at large numbers (much like we do for horses and other stock animals) rather than just treating every 3 months. Pets can tolerate low numbers of worms naturally.
And if these changes alone are not fixing the problem, try:
• consider using rain water for drinking rather than chlorinated and fluoride treated tap water.
• Make anyone adjustments to your home and backyard environment that are feasible - try and avoid using harsh chemical sprays or cleaning agents
• When an animals skin is inflamed, avoid using shampoos and medicated washes, they often supply only temporary relief, and may categorically be "contributing" to the ongoing cycle.
My experience, gained over the last 15 years in practice, has shown me that more than 70% of allergic pets can be maintained on a drug free regime if they supervene these guidelines. The extreme goal is to get your pet off all ongoing medications and treatments (especially cortisone) - even if they have the occasional itch.
Allergies in Dogs and Cats - simple Solutions That Work
